F7H( —— )

Catalog No. M37056 CAS No. 897109-93-2

F7H is a potent Frizzled receptor FZD7 antagonist with an IC50 value of 1.25 μM.F7H is a potent ligand for the transmembrane structural domain (TMD) of FZD7, with potential antitumor and bacteriostatic activity.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

F7H
Note

Research use only, not for human use.
Brief Description

F7H is a potent Frizzled receptor FZD7 antagonist with an IC50 value of 1.25 μM.F7H is a potent ligand for the transmembrane structural domain (TMD) of FZD7, with potential antitumor and bacteriostatic activity.
Description

F7H is a Frizzled receptor FZD7 antagonist (IC50: 1.25 μM). Frizzled receptors (FZDs) influence Wnt signaling, mediating embryonic development and tissue homeostasis. F7H is a potent ligand for the FZD7 transmembrane domain (TMD).
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

GPCR/G Protein
Target

Antibacterial
Recptor

Antibacterial | Wnt/beta-catenin
Research Area

——
Indication

——

Chemical Information

CAS Number

897109-93-2
Formula Weight

463.55
Molecular Formula

C24H18FN3O2S2
Purity

>98% (HPLC)
Solubility

——
SMILES

O=C(NC1=CC=C(SCC(=O)NC2=NC(=CS2)C=3C=CC=CC3)C=C1)C4=CC=C(F)C=C4
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Li C, et al. Structure-Based Ligand Discovery Targeting the Transmembrane Domain of Frizzled Receptor FZD7. J Med Chem. 2023 Sep 14;66(17):11855-11868.. .?

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