Cart
sales@molnova.com
Tubulin polymerization-IN-47
CAS No. 2834087-62-4
Tubulin polymerization-IN-47( —— )
Catalog No. M37020 CAS No. 2834087-62-4
Tubulin polymerization-IN-47 is a tubulin polymerization inhibitor and mitotic inhibitor with antitumor activity and inhibitory effects on neuroblastoma cancer cell proliferation, with IC50s of 7 and 12 nM for Chp-134 and Kelly cell lines, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 30 | In Stock |
|
| 5MG | 51 | In Stock |
|
| 10MG | 86 | In Stock |
|
| 25MG | 171 | In Stock |
|
| 50MG | 269 | In Stock |
|
| 100MG | 373 | In Stock |
|
| 200MG | 503 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameTubulin polymerization-IN-47
-
NoteResearch use only, not for human use.
-
Brief DescriptionTubulin polymerization-IN-47 is a tubulin polymerization inhibitor and mitotic inhibitor with antitumor activity and inhibitory effects on neuroblastoma cancer cell proliferation, with IC50s of 7 and 12 nM for Chp-134 and Kelly cell lines, respectively.
-
DescriptionTubulin polymerization-IN-47 (Compound 4h) is a tubulin polymerization inhibitor and mitotic inhibitor. Tubulin polymerization-IN-47 inhibits neuroblastoma cancer cell proliferation, with IC50s of 7 and 12 nM for Chp-134 and Kelly cell line.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorMicrotubule Associated
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2834087-62-4
-
Formula Weight375.42
-
Molecular FormulaC22H21N3O3
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 125 mg/mL (332.96 mM; Ultrasonic (<60°C)
-
SMILESO(C)C=1C=C(C=2C=3N(C=C(N3)C4=CC=C(C)C=C4)C=CN2)C=C(OC)C1OC
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Joshua Thammathong, et al. Fused Imidazopyrazine-Based Tubulin Polymerization Inhibitors Inhibit Neuroblastoma Cell Function. ACS Med. Chem. Lett. 2023.
molnova catalog
related products
-
Tricine
Tricine can clearly visualize tumors, may as melanoma imaging agents. Using the combination of tricine and a phosphine ligand, HYNIC-derivatized peptides or other small molecules can be labeled with 99mTc in high specific activity and with high stability for potential use as radiopharmaceuticals.
-
（3S,4R,17R,20S)-17-H...
（3S,4R,17R,20S)-17-Hydroxy-3-O-β-D-glucopyranosyl（1→2）-β-D-glucopyranosyl-28-O-β-D-glucopyranosyl-21,24-epoxybaccharane
-
Lycobetaine
Ungeremine is a potential biofungicide against Penicillium roqueforti and Aspergillus niger.Ungeremine have strong antibacterial activity against Flavobacterium columnare.
