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BCPA

CAS No. 547731-67-9

BCPA( —— )

Catalog No. M36956 CAS No. 547731-67-9

BCPA is a non-cytotoxic Pin1 modulator.BCPA modulates osteoclast activation and attenuates the reduction of Pin1 protein, thereby inhibiting RANKL-induced receptor activators of osteoclastogenesis.BCPA is used in the study of osteoporosis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 32 In Stock
10MG 51 In Stock
25MG 110 In Stock
50MG 173 In Stock
100MG 277 In Stock
200MG 390 In Stock
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Biological Information

  • Product Name
    BCPA
  • Note
    Research use only, not for human use.
  • Brief Description
    BCPA is a non-cytotoxic Pin1 modulator.BCPA modulates osteoclast activation and attenuates the reduction of Pin1 protein, thereby inhibiting RANKL-induced receptor activators of osteoclastogenesis.BCPA is used in the study of osteoporosis.
  • Description
    BCPA is a Pin1 regulator without cytotoxicity. BCPA attenuates the reduction of Pin1 protein to inhibit receptor activator of RANKL-induced osteoclastogenesis. BCPA regulates osteoclast activation, used to osteoporosis research.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    547731-67-9
  • Formula Weight
    417.33
  • Molecular Formula
    C22H22Cl2N2O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 6.67 mg/mL (15.98 mM; Ultrasonic (<80°C)
  • SMILES
    C(=CC(NCCCCNC(C=CC1=C(Cl)C=CC=C1)=O)=O)C2=C(Cl)C=CC=C2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Cho E, et al. BCPA {N, N′-1, 4-Butanediylbis [3-(2-chlorophenyl) acrylamide]} Inhibits osteoclast differentiation through increased retention of peptidyl-prolyl cis-trans isomerase never in mitosis A-interacting 1[J]. International Journal of Molecular Sciences, 2018, 19(11): 3436.
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