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AOH1996
CAS No. 2089314-64-5
AOH1996( —— )
Catalog No. M36932 CAS No. 2089314-64-5
AOH1996 is an orally active ligand for the replicasome component PCNA (proliferating cell nuclear antigen), targeting the transcription-replication conflict (TRC).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 91 | Get Quote |
|
| 5MG | 140 | Get Quote |
|
| 10MG | 217 | Get Quote |
|
| 25MG | 426 | Get Quote |
|
| 50MG | 638 | Get Quote |
|
| 100MG | 887 | Get Quote |
|
| 500MG | 1773 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameAOH1996
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NoteResearch use only, not for human use.
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Brief DescriptionAOH1996 is an orally active ligand for the replicasome component PCNA (proliferating cell nuclear antigen), targeting the transcription-replication conflict (TRC).
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DescriptionAOH1996 is an orally active ligand for the replicasome component PCNA (proliferating cell nuclear antigen), targeting the transcription-replication conflict (TRC). It interferes with the interaction of PCNA with its binding proteins, leading to DNA replication stress and apoptosis. AOH1996 causes proteasome-dependent rpb1 degradation and lethal DNA damage by stabilizing the interaction between PCNA and RNA polymerase II, and acts synergistically with DNA damaging agents to inhibit tumor cell growth.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayApoptosis
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TargetApoptosis
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RecptorApoptosis | DNA
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Research Area——
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Indication——
Chemical Information
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CAS Number2089314-64-5
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Formula Weight426.46
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Molecular FormulaC26H22N2O4
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Purity>98% (HPLC)
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Solubility——
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SMILESC(NCC(NC1=C(OC2=CC(OC)=CC=C2)C=CC=C1)=O)(=O)C=3C4=C(C=CC3)C=CC=C4
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
molnova catalog
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