Cart
sales@molnova.com
WDR5-IN-6
CAS No. 326901-92-2
WDR5-IN-6( —— )
Catalog No. M36914 CAS No. 326901-92-2
WDR5-IN-6 is a WDR5 inhibitor targeting the WBM locus and is highly synergistic with OICR-9429, a WDR5 inhibitor that targets the WIN locus.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 85 | In Stock |
|
| 10MG | 140 | In Stock |
|
| 25MG | 281 | In Stock |
|
| 50MG | 445 | In Stock |
|
| 100MG | 710 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 1442 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameWDR5-IN-6
-
NoteResearch use only, not for human use.
-
Brief DescriptionWDR5-IN-6 is a WDR5 inhibitor targeting the WBM locus and is highly synergistic with OICR-9429, a WDR5 inhibitor that targets the WIN locus.
-
DescriptionWDR5-IN-6 is a WDR5 inhibitor, targeting to WBM site. WDR5-IN-6 inhibits cell proliferation of neuroblastoma cell lines with potent anti-tumor activity. WDR5-IN-6 shows high synergy with OICR-9429 (HY-16993), a WDR5 inhibitor targeting to WIN site. WDR5-IN-6 can be used for reasearch in neuroblastoma.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayAngiogenesis
-
TargetJAK
-
RecptorJAK
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number326901-92-2
-
Formula Weight327.19
-
Molecular FormulaC13H8Cl2N2O2S
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 100 mg/mL (305.63 mM; Ultrasonic )
-
SMILESS(=O)(=O)(N1C=2C(N=C1)=CC=CC2)C3=C(Cl)C=CC(Cl)=C3
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Han QL, et al. Discovery, evaluation and mechanism study of WDR5-targeted small molecular inhibitors for neuroblastoma. Acta Pharmacol Sin. 2023 Apr;44(4):877-887.?
molnova catalog
related products
-
SAR-20347
SAR-20347 (SAR20347) is a potent, selective inhibitor of JAK1 and Tyk2 with IC50 of 59 and 13 nM in TR-FRET assays.
-
CEP-33779
CEP-33779 is a novel, selective, and orally bioavailable inhibitor of JAK2 with an IC50 of 1.8±0.6 nM.
-
WYE-151650
WYE-151650 is a novel potent, selective JAK3 inhibitor with IC50 of 0.8 nM, displays 36-, 14-, and 34-fold selectivity against JAK-1, JAK-2, and Tyk-2, respectively.
