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WDR5-IN-6

CAS No. 326901-92-2

WDR5-IN-6( —— )

Catalog No. M36914 CAS No. 326901-92-2

WDR5-IN-6 is a WDR5 inhibitor targeting the WBM locus and is highly synergistic with OICR-9429, a WDR5 inhibitor that targets the WIN locus.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 58 In Stock
5MG 85 In Stock
10MG 140 In Stock
25MG 272 In Stock
50MG 440 In Stock
100MG 687 In Stock
500MG 1395 In Stock
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Biological Information

  • Product Name
    WDR5-IN-6
  • Note
    Research use only, not for human use.
  • Brief Description
    WDR5-IN-6 is a WDR5 inhibitor targeting the WBM locus and is highly synergistic with OICR-9429, a WDR5 inhibitor that targets the WIN locus.
  • Description
    WDR5-IN-6 is a WDR5 inhibitor, targeting to WBM site. WDR5-IN-6 inhibits cell proliferation of neuroblastoma cell lines with potent anti-tumor activity. WDR5-IN-6 shows high synergy with OICR-9429 (HY-16993), a WDR5 inhibitor targeting to WIN site. WDR5-IN-6 can be used for reasearch in neuroblastoma.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    JAK
  • Recptor
    JAK
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    326901-92-2
  • Formula Weight
    327.19
  • Molecular Formula
    C13H8Cl2N2O2S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (305.63 mM; Ultrasonic )
  • SMILES
    S(=O)(=O)(N1C=2C(N=C1)=CC=CC2)C3=C(Cl)C=CC(Cl)=C3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Han QL, et al. Discovery, evaluation and mechanism study of WDR5-targeted small molecular inhibitors for neuroblastoma. Acta Pharmacol Sin. 2023 Apr;44(4):877-887.?
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