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Racotumomab
CAS No. 946832-34-4
Racotumomab( —— )
Catalog No. M36898 CAS No. 946832-34-4
Racotumomab (Anti-Human NGcGM3 Recombinant Antibody) is a mouse γ-type anti-recombinant antibody that specifically induces an antibody response against Neu-glycolyl GM3 ganglioside (NeuGcGM3), overexpressed in various solid tumors.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
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Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 471 | In Stock |
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| 10MG | 755 | In Stock |
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| 25MG | 1121 | In Stock |
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| 50MG | 1469 | In Stock |
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| 100MG | 2009 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameRacotumomab
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NoteResearch use only, not for human use.
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Brief DescriptionRacotumomab (Anti-Human NGcGM3 Recombinant Antibody) is a mouse γ-type anti-recombinant antibody that specifically induces an antibody response against Neu-glycolyl GM3 ganglioside (NeuGcGM3), overexpressed in various solid tumors.
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DescriptionRacotumomab (Anti-Human NGcGM3 Recombinant Antibody) is an anti-idiotype monoclonal antibody (MAb). Racotumomab reacts to Neu-glycolyl (NeuGc)-containing gangliosides, sulfatides, and other antigens expressed in tumors. Racotumomab is an active anticancer agent for lung cancer.
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In VitroRacotumomab induces a specific humoral and cellular immune response against the NeuGcGM3 ganglioside present in tumor cells, stimulating the cell death.
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In VivoRacotumomab (50 μg/dose, i.p.) together with Keyhole limpet hemocyanin (KLH) inhibits tumor growth in F3II cell (s.c.) mammary tumor mice model.Racotumomab (50 μg/dose, s.c.) together with Pemetrexed (100 mg/kg) is highly effective against lung nodules in 3LL cell (s.c.) mice xenograft.Racotumomab (50-200 μg/dose, s.c.) shows no significant antitumor effect in 3LL cell (s.c.) mice xenograft.Animal Model:3LL cell (s.c.) mice xenograftDosage:50 μg/dose, together with Pemetrexed (100 mg/kg)Administration:Subcutaneous injection (s.c.)Result:Reduced lung nodules.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number946832-34-4
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Formula Weight
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Molecular Formula——
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Vázquez AM, et al. Racotumomab: an anti-idiotype vaccine related to N-glycolyl-containing gangliosides - preclinical and clinical data. Front Oncol. 2012 Oct 23;2:150. ?
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