Oxelumab

Research use only, not for human use.

Oxelumab (R 4930) is a human monoclonal antibody targeting OX40L, and could be used to study asthma.

Oxelumab (R 4930) is a human monoclonal antibody against the OX40 ligand (OX40L). Oxelumab can be used for the research of asthma.

Cell Proliferation Assay Cell Line:Natural Killer (NK) cell lines Concentration:10 μg/mL Incubation Time:3 days Result:Inhibited cell proliferation of NK cells.

Animal Model:NSG mice with PBMCs from UC patients with simple clinical colitis activity index (SCCAI) Dosage:5 and 30 mg/kg Administration:Intraperitoneal injectionon; 5 and 30 mg/kg, once daily, on days 6 and 13 Result:Reversed the ethanol-induced colon dilated and the lost of distinct pattern of pellets. Decreased the level of IL-6 and increased the concentrations of glutamic acid. Reduced frequencies of splenic human effector memory T cells and switched B cells.

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Others

Other Targets

Interleukin

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1186098-83-8

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>98% (HPLC)

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(-20℃)

With Ice Pack

≥ 2 years