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Volagidemab

CAS No. 1233956-13-2

Volagidemab( —— )

Catalog No. M36755 CAS No. 1233956-13-2

Volagidemab, a monoclonal antibody (mAb) that antagonizes the glucagon receptor (GCGR), is utilized in researching Type 1 Diabetes (T1D) .

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Volagidemab
  • Note
    Research use only, not for human use.
  • Brief Description
    Volagidemab, a monoclonal antibody (mAb) that antagonizes the glucagon receptor (GCGR), is utilized in researching Type 1 Diabetes (T1D) .
  • Description
    Volagidemab is an antagonistic glucagon receptor (GCGR) monoclonal antibody (mAb).Volagidemab can be used in the research of type 1 diabetes (T1D).
  • In Vitro
    ——
  • In Vivo
    Animal Model:Alloxan-induced diabetic mice Dosage:5 mg/kg Administration:Subcutaneous injection (s.c.)Result:Reduced phosphorylated CREB protein and PEPCK protein expression to nondiabetic levels.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1233956-13-2
  • Formula Weight
  • Molecular Formula
    ——
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Pettus J, et al. Glucagon receptor antagonist volagidemab in type 1 diabetes: a 12-week, randomized, double-blind, phase 2 trial. Nat Med. 2022 Oct;28(10):2092-2099. ?
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