ATP dimagnesium

Research use only, not for human use.

ATP dimagnesium is an important substance for energy storage and metabolism in the body and is involved in the energy cycle and metabolism of the body.

ATP (Adenosine 5'-triphosphate) dimagnesium is a central component of energy storage and metabolism in vivo. ATP dimagnesium provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP dimagnesium is an important endogenous signaling molecule in immunity and inflammation.

ATP (5 mM; 1 hour) co-treatment with LPS (1 μg/mL) has a synergistic effect on the activation of the NLRP3 inflammasome in HGFs.ATP (2 mM; 0.5-24 hours) induces secretion of IL-1β, KC and MIP-2 from BMDMs in a caspase-1 activation-dependent manner.ATP promotes neutrophil chemotaxis in vitro.

ATP (50 mg/kg; i.p.) protects mice against bacterial infection in vivo.ATP induces the secretion of IL-1β, KC and MIP-2 and neutrophils recruitment in vivo.Animal Model:Four-week-old Kunming mice (18-22 g)Dosage:50 mg/kg Administration: Intraperitoneal injection, before bacterial (E. coli) challenge Result:Protected mice from bacterial infection.

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Others

Other Targets

Others

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74804-12-9

551.76

C10H12Mg2N5O13P3

>98% (HPLC)

In Vitro:?H2O : 250 mg/mL (453.10 mM; Ultrasonic)

[Mg++].[Mg++].Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O)[C@@H](O)[C@H]1O

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(-20℃)

With Ice Pack

≥ 2 years