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SLC26A3-IN-2
CAS No. 950348-60-4
SLC26A3-IN-2( —— )
Catalog No. M36614 CAS No. 950348-60-4
SLC26A3-IN-2 is an orally active compound that functions as an inhibitor of the anion exchanger protein SLC26A3, with an IC50 of 360 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 120 | In Stock |
|
| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameSLC26A3-IN-2
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NoteResearch use only, not for human use.
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Brief DescriptionSLC26A3-IN-2 is an orally active compound that functions as an inhibitor of the anion exchanger protein SLC26A3, with an IC50 of 360 nM.
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DescriptionSLC26A3-IN-2 is an orally active inhibitor of anion exchanger protein SLC26A3 (IC50=360 nM). SLC26A3 belongs to solute carrier (SLC) proteins, and the SLC26 family. SLC26 family has broad anion specificity for chloride, bicarbonate, sulfate and oxalate. SLC26A3 down-regulates in adenoma, DRA, involves in in intestinal absorption of chloride and oxalate. The loss of SLC26A3 function mutations is associated with chloride-losing diarrhea.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number950348-60-4
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Formula Weight368.84
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Molecular FormulaC19H13ClN2O2S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 16.67 mg/mL (45.20 mM; Ultrasonic (<60°C)
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SMILESO=C1N2C(=CSC2=NC(COC3=C(Cl)C=CC=C3)=C1)C4=CC=CC=C4
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Cil O, et al. Small molecule inhibitors of intestinal epithelial anion exchanger SLC26A3 (DRA) with a luminal, extracellular site of action. Eur J Med Chem. 2023 Mar 5;249:115149.?
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