JPD447( —— )

Catalog No. M36587 CAS No. 2883235-86-5

JPD447 is a MAC-0547630 derivative that potentiates UppS inhibitors of β-lactam antibiotics with antimicrobial activity and can be used to study bacterial infections.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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10MG	216	In Stock
25MG	434	In Stock
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Biological Information

Product Name

JPD447
Note

Research use only, not for human use.
Brief Description

JPD447 is a MAC-0547630 derivative that potentiates UppS inhibitors of β-lactam antibiotics with antimicrobial activity and can be used to study bacterial infections.
Description

JPD447, a MAC-0547630 derivative, is a novel class of UppS inhibitor to potentiate β-lactam antibiotics.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

GPCR/G Protein
Target

Antibacterial
Recptor

Antibacterial
Research Area

——
Indication

——

Chemical Information

CAS Number

2883235-86-5
Formula Weight

338.42
Molecular Formula

C20H23FN4
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (295.49 mM; Ultrasonic (<80°C)
SMILES

FC1=CC=C(C=C1)C=2C=NN3C2N=C(C=C3N4CCCCCC4)CC
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Workman SD, et al. Structural Insights into the Inhibition of Undecaprenyl Pyrophosphate Synthase from Gram-Positive Bacteria. J Med Chem. 2021 Sep 23;64(18):13540-13550. ?

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