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Nortriptyline

CAS No. 72-69-5

Nortriptyline( —— )

Catalog No. M36573 CAS No. 72-69-5

Nortriptyline is an antidepressant compound that enhances corticosteroid sensitivity of blood T-cells in patients with chronic obstructive pulmonary disease (COPD) and may be used for smoking cessation.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 93 In Stock
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Biological Information

  • Product Name
    Nortriptyline
  • Note
    Research use only, not for human use.
  • Brief Description
    Nortriptyline is an antidepressant compound that enhances corticosteroid sensitivity of blood T-cells in patients with chronic obstructive pulmonary disease (COPD) and may be used for smoking cessation.
  • Description
    Nortriptyline (Desmethylamitriptyline), the main active metabolite of Amitriptyline, is a tricyclic antidepressant. Nortriptyline is a potent autophagy inhibitor and has anticancer effects. N
  • In Vitro
    ——
  • In Vivo
    Animal Model:Adult male C3H/HeN mice (25-30 g; 2-3 months of age) injected with MBT-2 cells Dosage:10 or 20 mg/kg Administration:Intraperitoneal injection; every day; for three weeks.Result:Suppressed tumor growth in mice inoculated with MBT-2 cells.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    72-69-5
  • Formula Weight
    263.38
  • Molecular Formula
    C19H21N
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C=1C=CC2=C(C1)C(=CCCNC)C=3C=CC=CC3CC2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Dean L. Amitriptyline Therapy and CYP2D6 and CYP2C19 Genotype. In: Pratt VM, Scott SA, Pirmohamed M, et al., eds. Medical Genetics Summaries. Bethesda (MD): National Center for Biotechnology Information (US); March 23, 2017.?
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