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TH-Z93
CAS No. 2260887-09-8
TH-Z93( —— )
Catalog No. M36537 CAS No. 2260887-09-8
TH-Z93 is a potent FPPS inhibitor (IC50:90 nM) and a lipophilic bisphosphonate.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 297 | In Stock |
|
| 10MG | 432 | In Stock |
|
| 25MG | 655 | In Stock |
|
| 50MG | 886 | In Stock |
|
| 100MG | 1190 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 2390 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameTH-Z93
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NoteResearch use only, not for human use.
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Brief DescriptionTH-Z93 is a potent FPPS inhibitor (IC50:90 nM) and a lipophilic bisphosphonate.
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DescriptionTH-Z93, a lipophilic bisphosphonate, is a FPPS inhibitor (IC50: 90 nM).
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In Vitro——
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In VivoTH-Z93 (20 μg, i.p.) exhibits strong prophylactic effects in a pathogenic influenza model.Animal Model:B16-OVA cells (s.c.) xenograft mice model.Dosage:20 μg Administration:Intraperitoneal injection (i.p.)Result:Inhibited tumor growth and prolonged survival.
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Synonyms——
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PathwayGPCR/G Protein
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TargetAntibacterial
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RecptorAntibacterial
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Research Area——
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Indication——
Chemical Information
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CAS Number2260887-09-8
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Formula Weight368.26
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Molecular FormulaC12H22N2O7P2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?H2O : 1.89 mg/mL (5.13 mM; ultrasonic and warming and adjust pH to 10 with NaOH and heat to 60°C)
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SMILESC(NC1=CC(OCCCCCC)=CC=N1)(P(=O)(O)O)P(=O)(O)O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Xia Y, et al. The Mevalonate Pathway Is a Druggable Target for Vaccine Adjuvant Discovery. Cell. 2018 Nov 1;175(4):1059-1073.e21. ?
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