Moiramide B( —— )

Catalog No. M36494 CAS No. 155233-31-1

Moiramide B is a potent acetyl coenzyme A carboxylase (ACC) inhibitor (IC50:6 nM) with antimicrobial activity, strongly inhibiting Gram-positive bacteria but weakly inhibiting Gram-negative bacteria.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

Moiramide B
Note

Research use only, not for human use.
Brief Description

Moiramide B is a potent acetyl coenzyme A carboxylase (ACC) inhibitor (IC50:6 nM) with antimicrobial activity, strongly inhibiting Gram-positive bacteria but weakly inhibiting Gram-negative bacteria.
Description

Moiramide B is a potent acetyl-CoA carboxylase (ACC) inhibitor with an IC50 value of 6 nM. Moiramide B has antibacterial activity.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Acetyl-CoA Carboxylase | Antibiotic
Research Area

——
Indication

——

Chemical Information

CAS Number

155233-31-1
Formula Weight

453.53
Molecular Formula

C25H31N3O5
Purity

>98% (HPLC)
Solubility

——
SMILES

C([C@@H](NC(C[C@H](NC(/C=C/C=C/C)=O)C1=CC=CC=C1)=O)[C@@H](C)C)(=O)[C@H]2[C@H](C)C(=O)NC2=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Cifone MT, et, al. Heterobivalent Inhibitors of Acetyl-CoA Carboxylase: Drug Target Residence Time and Time-Dependent Antibacterial Activity. J Med Chem. 2022 Dec 22;65(24):16510-16525.??

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