SFI003

CAS No. 2361332-90-1

SFI003( —— )

Catalog No. M36429 CAS No. 2361332-90-1

SFI003 is a novel SRSF3 inhibitor that exerts anticancer activity against colorectal cancer by modulating the SRSF3 / DHCR24 / ROS axis and driving apoptosis in CRC cells through the SRSF3 / DHCR24 / reactive oxygen species (ROS) axis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 176 In Stock
5MG 167 In Stock
10MG 269 In Stock
25MG 523 In Stock
50MG 737 In Stock
100MG 1004 In Stock
200MG 1386 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    SFI003
  • Note
    Research use only, not for human use.
  • Brief Description
    SFI003 is a novel SRSF3 inhibitor that exerts anticancer activity against colorectal cancer by modulating the SRSF3 / DHCR24 / ROS axis and driving apoptosis in CRC cells through the SRSF3 / DHCR24 / reactive oxygen species (ROS) axis.
  • Description
    SFI003 is a novel SRSF3 inhibitor that exerts anticancer activity against colorectal cancer by modulating the SRSF3 / DHCR24 / ROS axis and driving apoptosis in CRC cells through the SRSF3 / DHCR24 / reactive oxygen species (ROS) axis.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Immunology/Inflammation
  • Target
    ROS
  • Recptor
    ROS | Apoptosis
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2361332-90-1
  • Formula Weight
    363.44
  • Molecular Formula
    C19H17N5OS
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(=N\NC1=NC(=CS1)C2=CC=C(OC)C=C2)(\C)/C=3NC=4C(N3)=CC=CC4
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

molnova catalog
related products
  • DS-6051b

    DS-6051b is a new-generation selective inhibitor of ROS1/NTRK including ROS1,NTRK1,NTRK2 and NTRK3 with IC50 of 0.207 nM,0.622 nM,2.28 nM and 0.980 nM, respectively.DS-6051b inhibited the growth of the ROS1 fusion-positive HCC78 cancer cell line and the CD74-ROS1 overexpressed Ba/F3 cells.

  • Heme Oxygenase-1-IN-...

    HO-1-IN-1 is a heme oxygenase 1 (HO-1) inhibitor (IC50: 250 nM).

  • Ophiopogonin D(b)

    Ophiopogonin D(OPD) significantly inhibited the in vitro and in vivo growth of prostate cells via RIPK1 OPD may be developed as a potential anti-prostate cancer agent.