PI5P4Ks-IN-2( —— )

Catalog No. M36403 CAS No. 2766854-03-7

PI5P4Ks-IN-2 is an inhibitor of the phosphatidylinositol 5-phosphate 4-kinase PI5P4Kγ.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

PI5P4Ks-IN-2
Note

Research use only, not for human use.
Brief Description

PI5P4Ks-IN-2 is an inhibitor of the phosphatidylinositol 5-phosphate 4-kinase PI5P4Kγ.
Description

PI5P4Ks-IN-2 is a inhibitor of phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ). PI5P4Ks-IN-2 targets to PI5P4K isoforms with pIC50 values of <4.3 (PI5P4Kα), <4.6 (PI5P4Kβ), 6.2 (PI5P4Kγ), 0.32 (PI5P4Kγ+), respectively.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

PI3K/Akt/mTOR signaling
Target

PI3K
Recptor

PI3K
Research Area

——
Indication

——

Chemical Information

CAS Number

2766854-03-7
Formula Weight

357.45
Molecular Formula

C22H23N5
Purity

>98% (HPLC)
Solubility

——
SMILES

N(CC1=CC=CC=N1)C2=C3C(=NC(=N2)C4=C(C(C)C)C=CC=C4)C=CN3C
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Boffey HK, et al. Development of Selective Phosphatidylinositol 5-Phosphate 4-Kinase γ Inhibitors with a Non-ATP-competitive, Allosteric Binding Mode. J Med Chem. 2022 Feb 24;65(4):3359-3370. ?

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