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Bisindolylmaleimide VIII

CAS No. 125313-65-7

Bisindolylmaleimide VIII( —— )

Catalog No. M36363 CAS No. 125313-65-7

Bisindolylmaleimide VIII (Ro-31-7549) is a selective and potent protein kinase C (PKC) inhibitor with good inhibition of PKC-α, PKC-β I, PKC-β II, PKC-γ, and PKC-ε.

Purity : >98% (HPLC)

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Biological Information

Product Name

Bisindolylmaleimide VIII
Note

Research use only, not for human use.
Brief Description

Bisindolylmaleimide VIII (Ro-31-7549) is a selective and potent protein kinase C (PKC) inhibitor with good inhibition of PKC-α, PKC-β I, PKC-β II, PKC-γ, and PKC-ε.
Description

Bisindolylmaleimide VIII (Ro-31-7549) is a selective and potent protein kinase C (PKC) inhibitor with good inhibition of PKC-α, PKC-β I, PKC-β II, PKC-γ, and PKC-ε.Bisindolylmaleimide VIII Bisindolylmaleimide VIII inhibits T cell-mediated autoimmune diseases and enhances Fas-mediated apoptosis through a protein kinase C-independent mechanism.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Angiogenesis
Target

PKC
Recptor

PKC | Apoptosis
Research Area

——
Indication

——

Chemical Information

CAS Number

125313-65-7
Formula Weight

398.46
Molecular Formula

C24H22N4O2
Purity

>98% (HPLC)
Solubility

——
SMILES

O=C1NC(=O)C(C2=CN(C=3C=CC=CC23)CCCN)=C1C4=CN(C=5C=CC=CC45)C
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

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