DSP-0565 exhibits anti-convulsant activity and good safety margin in various models including scPTZ, 6 Hz, MES, and amygdala kindling.

KL-50 is a selective toxin toward tumors that lack the DNA repair protein O6-methylguanine-DNA-methyltransferase (MGMT), which reverses the formation of O6-alkylguanine lesions. KL-50 activates DNA damage response pathways and cycle arrest in MGMT-cells, independent of mismatch repair (MMR). KL-50 is promising for research of brain tumors that lack the DNA repair protein MGMT.

Pantolactone belongs to the class of organic compounds known as gamma-butyrolactones. gamma-Butyrolactones are compounds containing a gamma-butyrolactone moiety which consists of an aliphatic five-member ring with four carbon atoms one oxygen atom and bears a ketone group on the carbon adjacent to the oxygen atom.