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PDE5-IN-9

CAS No. 157862-84-5

PDE5-IN-9( —— )

Catalog No. M36099 CAS No. 157862-84-5

PDE5-IN-9 inhibits Phosphodiesterase PDE1c and is used to treat hypertension, heart failure, myocardial infarction, kidney failure, asthma, bronchitis, and dementia.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 41 In Stock
25MG 67 In Stock
50MG 99 In Stock
100MG 146 In Stock
200MG 216 In Stock
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Biological Information

  • Product Name
    PDE5-IN-9
  • Note
    Research use only, not for human use.
  • Brief Description
    PDE5-IN-9 inhibits Phosphodiesterase PDE1c and is used to treat hypertension, heart failure, myocardial infarction, kidney failure, asthma, bronchitis, and dementia.
  • Description
    PDE5-IN-9 (Compound 59) is a PDE5 inhibitor (IC50: 11.2 μM). PDE5-IN-9 shows interaction with Gln 817, Tyr 612, and Ala 767 amino acid residues. PDE5-IN-9 can be used for research of cardiovascular disease.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    PDE
  • Recptor
    PDE
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    157862-84-5
  • Formula Weight
    318.4
  • Molecular Formula
    C18H14N4S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    N(CC1=CC=CS1)C=2C3=C(N=C(N2)C=4C=CC=NC4)C=CC=C3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Sarvesh Paliwal, et al. Pharmacophore and molecular docking based identification of novel structurally diverse PDE-5 inhibitors. Medicinal Chemistry Research. 2015, 24, 576-587.
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