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BAY-4931
CAS No. 423150-91-8
BAY-4931( —— )
Catalog No. M36091 CAS No. 423150-91-8
BAY-4931 is a powerful, covalent, and selective inverse-agonist of PPARγ, exhibiting an IC50 value of 0.17 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 93 | In Stock |
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| 5MG | 76 | In Stock |
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| 10MG | 122 | In Stock |
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| 25MG | 275 | In Stock |
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| 50MG | 423 | In Stock |
|
| 100MG | 625 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 1330 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameBAY-4931
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NoteResearch use only, not for human use.
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Brief DescriptionBAY-4931 is a powerful, covalent, and selective inverse-agonist of PPARγ, exhibiting an IC50 value of 0.17 nM.
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DescriptionBAY-4931 is a potent, covalent and selective PPARγ inverse-agonist with an IC50 of 0.17 nM.
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In VitroBAY-4931 (0-10 μM; 7 days) inhibits UM-UC-9 proliferation with an IC50 of 3.4 nM.BAY-4931 only inhibits CYP2C8 in CYP inhibition test.Cell Proliferation Assay Cell Line:UM-UC-9 cells Concentration:0-10 μM Incubation Time:7 days Result:Inhibited proliferation with an IC50 of 3.4 nM.
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In Vivo——
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetPPAR
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RecptorPPAR
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Research Area——
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Indication——
Chemical Information
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CAS Number423150-91-8
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Formula Weight421.83
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Molecular FormulaC22H16ClN3O4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (296.33 mM; Ultrasonic (<70°C)
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SMILESN(C(=O)C1=CC(N(=O)=O)=CC=C1Cl)C=2C=C3C(OC(=N3)C4=CC=C(CC)C=C4)=CC2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Orsi DL, et al. Discovery and Structure-Based Design of Potent Covalent PPARγ Inverse-Agonists BAY-4931 and BAY-0069. J Med Chem. 2022 Nov 10;65(21):14843-14863.?
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