HDAC-IN-52

CAS No. 2075787-77-6

HDAC-IN-52( —— )

Catalog No. M36045 CAS No. 2075787-77-6

HDAC-IN-52, a pyridine-containing HDAC inhibitor, effectively inhibits HDAC1, HDAC2, HDAC3, and HDAC10 with IC50 values of 0.189, 0.227, 0.440, and 0.446 μM, respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 269 Get Quote
5MG 372 Get Quote
10MG 558 Get Quote
25MG 821 Get Quote
50MG 1122 Get Quote
100MG 1485 Get Quote
200MG 2007 Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    HDAC-IN-52
  • Note
    Research use only, not for human use.
  • Brief Description
    HDAC-IN-52, a pyridine-containing HDAC inhibitor, effectively inhibits HDAC1, HDAC2, HDAC3, and HDAC10 with IC50 values of 0.189, 0.227, 0.440, and 0.446 μM, respectively.
  • Description
    HDAC-IN-52 is a pyridine-containing HDAC inhibitor, with IC50s of 0.189, 0.227, 0.440 and 0.446 μM for HDAC1, HDAC2, HDAC3, and HDAC10, respectively. HDAC-IN-52 can be used for the research of cancer.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    HDAC
  • Recptor
    HDAC
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2075787-77-6
  • Formula Weight
    396.44
  • Molecular Formula
    C24H20N4O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(C(NC=1C=CC(C(NC2=C(N)C=CC=C2)=O)=NC1)=O)C3=CC4=C(C=C3)C=CC=C4
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Bello ED, et, al. Novel pyridine-containing histone deacetylase inhibitors strongly arrest proliferation, induce apoptosis and modulate miRNAs in cancer cells. Eur J Med Chem. 2022 Dec 15;247:115022.?
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