Cart
sales@molnova.com
hMAO-B-IN-4
CAS No. 1666119-75-0
hMAO-B-IN-4( —— )
Catalog No. M35968 CAS No. 1666119-75-0
hMAO-B-IN-4 is a selective, reversible and blood–brain barrier (BBB) penetrable inhibitor of human monoamine oxidase-B (hMAO-B, IC50=0.067 μM, Ki= 0.03 μM, hMAO-A, IC50= 33.82 μM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 42 | In Stock |
|
| 5MG | 36 | In Stock |
|
| 10MG | 55 | In Stock |
|
| 25MG | 112 | In Stock |
|
| 50MG | 183 | In Stock |
|
| 100MG | 300 | In Stock |
|
| 200MG | 428 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NamehMAO-B-IN-4
-
NoteResearch use only, not for human use.
-
Brief DescriptionhMAO-B-IN-4 is a selective, reversible and blood–brain barrier (BBB) penetrable inhibitor of human monoamine oxidase-B (hMAO-B, IC50=0.067 μM, Ki= 0.03 μM, hMAO-A, IC50= 33.82 μM).
-
DescriptionhMAO-B-IN-4 (compound B10) is a selective, reversible and blood–brain barrier (BBB) penetrable human monoamine oxidase-B (hMAO-B) inhibitor with an IC50 value and a Ki value of 0.067 and 0.03 μM, respectively. hMAO-B-IN-4 inhibits hMAO-A with an IC50 value of 33.82 μM. hMAO-B-IN-4 can be used for Alzheimer’s disease (AD) and Parkinson’s disease (PD) research.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayMetabolic Enzyme/Protease
-
TargetMAO
-
RecptorMAO
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1666119-75-0
-
Formula Weight320.4
-
Molecular FormulaC20H16O2S
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 50 mg/mL (156.05 mM; Ultrasonic )
-
SMILESO=C(\C=C\c1ccc(OCc2ccccc2)cc1)c1cccs1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Sudevan ST, et al. Introduction of benzyloxy pharmacophore into aryl/heteroaryl chalcone motifs as a new class of monoamine oxidase B inhibitors. Sci Rep. 2022 Dec 27;12(1):22404.?
molnova catalog
related products
-
hMAO-B-IN-32
hMAO-B-IN-32 is a potent hMAO-B selective inhibitor with an IC50 of 45.52 μM.
-
(2-Chloropyridin-4-y...
(2-Chloropyridin-4-yl)methanamine hydrochloride is a selective LOXL2 inhibitor(IC50 : 126 nM).
-
Esuprone
Esuprone (LU-43839) is a novel reversible and highly selective MAO-A inhibitor with anticonvulsant activity for the treatment of depression.
