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Tyrphostin AG 538

CAS No. 133550-18-2

Tyrphostin AG 538( —— )

Catalog No. M35935 CAS No. 133550-18-2

Tyrphostin AG 538 is a chalcone compound, an IGF-1 receptor kinase inhibitor (IC 0 : for 400 nM) that is potent, cell-permeable, reversible, and competitive.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
5MG	193	In Stock
10MG	292	In Stock
25MG	513	In Stock
50MG	686	In Stock
100MG	909	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

Tyrphostin AG 538
Note

Research use only, not for human use.
Brief Description

Tyrphostin AG 538 is a chalcone compound, an IGF-1 receptor kinase inhibitor (IC 0 : for 400 nM) that is potent, cell-permeable, reversible, and competitive.
Description

AG 538 is a potent, competitive inhibitor of IGF-1 receptor kinase, with an IC50 of 400 nM.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Angiogenesis
Target

IGF-1R
Recptor

IGF-1R
Research Area

——
Indication

——

Chemical Information

CAS Number

133550-18-2
Formula Weight

297.26
Molecular Formula

C16H11NO5
Purity

>98% (HPLC)
Solubility

——
SMILES

C(/C(=C/C1=CC(O)=C(O)C=C1)/C#N)(=O)C2=CC(O)=C(O)C=C2
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. G Blum, et al. Substrate Competitive Inhibitors of IGF-1 Receptor Kinase. Biochemistry. 2000 Dec 26;39(51):15705-12.?

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