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Adenosine 5-monophosphate disodium salt

CAS No. 4578-31-8

Adenosine 5-monophosphate disodium salt( —— )

Catalog No. M35884 CAS No. 4578-31-8

Adenosine 5'-monophosphate disodium salt (Adenosine Phosphate Disodium) is a purine nucleotide involved in ATP metabolism and is used to study the effects of ATP on cells and organisms.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Adenosine 5-monophosphate disodium salt
  • Note
    Research use only, not for human use.
  • Brief Description
    Adenosine 5'-monophosphate disodium salt (Adenosine Phosphate Disodium) is a purine nucleotide involved in ATP metabolism and is used to study the effects of ATP on cells and organisms.
  • Description
    Adenosine 5'-monophosphate disodium is an orally active purine nucleotide, and participates in ATP metabolism. Adenosine 5'-monophosphate disodium is also a ligand for adenosine 2B receptor. Adenosine 5'-monophosphate disodium can activate AMPK in skeletal muscle, and ameliorates insulin resistance and impaired glucose metabolism. Adenosine 5'-monophosphate disodium can be used for research of diabetes.
  • In Vitro
    ——
  • In Vivo
    Animal Model:C57BL/6 J mice with high-fat diet-induced diabetes Dosage:10 and 13 mg/L Administration:Added in distilled water, for 25 weeks Result:Enhanced phosphorylation of AMPK and mRNA levels of genes involved in lipid oxidation in the skeletal muscle.
  • Synonyms
    ——
  • Pathway
    Microbiology/Virology
  • Target
    Antibiotic
  • Recptor
    Nucleoside Antimetabolite/Analog
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    4578-31-8
  • Formula Weight
    391.18
  • Molecular Formula
    C10H12N5Na2O7P
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?H2O : 100 mg/mL (255.64 mM; Ultrasonic)
  • SMILES
    [Na+].[Na+].Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP([O-])([O-])=O)[C@@H](O)[C@H]1O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Ardiansyah, et al. Adenosine and adenosine-5'-monophosphate ingestion ameliorates abnormal glucose metabolism in mice fed a high-fat diet. BMC Complement Altern Med. 2018 Nov 14;18(1):304. ?
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