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Cuprizone
CAS No. 370-81-0
Cuprizone( —— )
Catalog No. M35850 CAS No. 370-81-0
Cuprizone is a copper chelator.Cuprizone is used to induce schizophrenia in mice.Cuprizone induces oligodendrocyte death and induces a demyelination response.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1G | 32 | In Stock |
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Biological Information
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Product NameCuprizone
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NoteResearch use only, not for human use.
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Brief DescriptionCuprizone is a copper chelator.Cuprizone is used to induce schizophrenia in mice.Cuprizone induces oligodendrocyte death and induces a demyelination response.
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DescriptionCuprizone is a copper chelating agent that forms a deep blue copper ketone complex with copper (II). The copper ketone reaction can be used in colorimetric tests for the presence of trace copper. Cuprizone can be used to induce some schizophrenia-like behavior in mice. Cuprizone acts on copper enzymes, including SOD1, cytochrome oxidase, and DβH, thereby causing oxidative stress and increasing DA levels in certain brain regions such as the medial prefrontal cortex (PFC).
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number370-81-0
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Formula Weight278.35
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Molecular FormulaC14H22N4O2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 6.67 mg/mL (23.96 mM; Ultrasonic (<60°C)
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SMILESO=C(NN=C1CCCCC1)C(=O)NN=C1CCCCC1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Suzuki K, et al. Status spongiosus of CNS and hepatic changes induced by cuprizone (biscyclohexanone oxalyldihydrazone). Am J Pathol. 1969 Feb;54(2):307-25. ?
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