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AZD0780

CAS No. 2455427-91-3

AZD0780( —— )

Catalog No. M35805 CAS No. 2455427-91-3

AZD0780 (EX-A6975) is an oral small molecule PCSK9 inhibitor being developed by AstraZeneca as a first-in-class treatment for patients with dyslipidemia that is uncontrolled with statins alone.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 167 In Stock
5MG 150 In Stock
10MG 236 In Stock
25MG 377 In Stock
50MG 529 In Stock
100MG 731 In Stock
200MG 1014 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    AZD0780
  • Note
    Research use only, not for human use.
  • Brief Description
    AZD0780 (EX-A6975) is an oral small molecule PCSK9 inhibitor being developed by AstraZeneca as a first-in-class treatment for patients with dyslipidemia that is uncontrolled with statins alone.
  • Description
    PCSK9-IN-12 is a heteroaryl compound. PCSK9-IN-12has bind affinity for PCSK9with a Kd value of ＜200 nM. PCSK9-IN-12 can be used for the research of cholesterol metabolism.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2455427-91-3
  • Formula Weight
    414.41
  • Molecular Formula
    C20H20F2N6O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (241.31 mM; Ultrasonic )
  • SMILES
    FC(F)Oc1cnc(N[C@H]2CC[C@@H](C2)Nc2ccc(cn2)-n2ccccc2=O)nc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Michael H. Serrano-Wu, et al. Pcsk9 inhibitors and methods of use thereof. Patent. WO2020150474A1.
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