Cart
sales@molnova.com
(+)-JNJ-A07
CAS No. 2135640-93-4
(+)-JNJ-A07( —— )
Catalog No. M35764 CAS No. 2135640-93-4
(+)-JNJ-A07 is a pan-serotypic dengue virus inhibitor that targets NS3-NS4B interaction with high potency. (+)-JNJ-A07 has antiviral activity and can be used to study dengue virus infections.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 188 | In Stock |
|
| 5MG | 150 | In Stock |
|
| 10MG | 236 | In Stock |
|
| 25MG | 377 | In Stock |
|
| 50MG | 529 | In Stock |
|
| 100MG | 731 | In Stock |
|
| 200MG | 1004 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product Name(+)-JNJ-A07
-
NoteResearch use only, not for human use.
-
Brief Description(+)-JNJ-A07 is a pan-serotypic dengue virus inhibitor that targets NS3-NS4B interaction with high potency. (+)-JNJ-A07 has antiviral activity and can be used to study dengue virus infections.
-
Description(+)-JNJ-A07 is a highly potent, orally active pan-serotype dengue virus inhibitor targeting the NS3-NS4B interaction. (+)-JNJ-A07 exerts nanomolar to picomolar activity against a panel of 21 clinical isolates. (+)-JNJ-A07 has a favourable pharmacokinetic profile that results in outstanding efficacy against dengue virus infection in mouse infection models.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorVirus Protease
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2135640-93-4
-
Formula Weight578.96
-
Molecular FormulaC28H26ClF3N2O6
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 100 mg/mL (172.72 mM; Ultrasonic )
-
SMILESC(C(NC1=CC(OCCCC(O)=O)=CC(OC)=C1)C2=CC=C(Cl)C=C2)(=O)N3C=4C(CC3)=CC=C(OC(F)(F)F)C4
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Kaptein SJF, et al. A pan-serotype dengue virus inhibitor targeting the NS3-NS4B interaction [published correction appears in Nature. 2021 Nov;599(7883):E2]. Nature. 2021;598(7881):504-509. ?
molnova catalog
related products
-
Secoisolariciresinol...
The heartwoods of Podocarpus spicata.
-
Acetyl-Amylin (8-37)...
Acetyl-Amylin (8-37) (human) is a specific amylin antagonist.
-
Phytolaccagenin
Phytolaccagenin, a triterpenoid saponin, is the active component of Radix Phtolaccae which are widely used in East Asian countries for the treatment of inflammation-related diseases.
