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BE1218
CAS No. 2893967-40-1
BE1218( —— )
Catalog No. M35749 CAS No. 2893967-40-1
BE1218 is a liver X receptor (LXR) inverse agonist, active on LXRα and LXRβ, with IC50 values of 9 nM and 7 nM, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 54 | In Stock |
|
| 5MG | 39 | In Stock |
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| 10MG | 62 | In Stock |
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| 25MG | 107 | In Stock |
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| 50MG | 155 | In Stock |
|
| 100MG | 226 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameBE1218
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NoteResearch use only, not for human use.
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Brief DescriptionBE1218 is a liver X receptor (LXR) inverse agonist, active on LXRα and LXRβ, with IC50 values of 9 nM and 7 nM, respectively.
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DescriptionBE1218 is a liver X receptor (LXR) inverse agonist with IC50 values of 9 nM and 7 nM against LXRα and LXRβ, respectively.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorLiver X Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number2893967-40-1
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Formula Weight551.69
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Molecular FormulaC30H30FNO4S2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 33.33 mg/mL (60.41 mM; Ultrasonic (<60°C)
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SMILESN(S(=O)(=O)C1=C(C)C=C(C)C=C1C)(CC2=CC=C(C=C2)C3=CC(S(C)(=O)=O)=CC=C3)CC4=C(F)C=CC=C4
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Elgendy B, et al. Synthesis and structure activity relationship of the first class of LXR inverse agonists. Bioorg Chem. 2022 Feb;119:105540.?
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