DX3-213B( —— )

Catalog No. M35700 CAS No. 2749555-66-4

DX3-213B is a potent, orally active inhibitor of oxidative phosphorylation (OXPHOS) complex I with an IC50 of 3.6 nM.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	180	In Stock
5MG	170	In Stock
10MG	275	In Stock
25MG	588	In Stock
50MG	833	In Stock
100MG	1135	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

Get Quotation Bulk Inquiry Add to Cart

Biological Information

Product Name

DX3-213B
Note

Research use only, not for human use.
Brief Description

DX3-213B is a potent, orally active inhibitor of oxidative phosphorylation (OXPHOS) complex I with an IC50 of 3.6 nM.
Description

DX3-213B is a highly potent, orally active oxidative phosphorylation (OXPHOS) complex I inhibitor (IC50=3.6 nM). DX3-213B impairs ATP generation (IC50=11 nM), and blocks MIA PaCa-2 cell growth (GI50=11 nM). DX3-213B is used for the research of the pancreatic cancer.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

OXPHOS
Research Area

——
Indication

——

Chemical Information

CAS Number

2749555-66-4
Formula Weight

478.57
Molecular Formula

C20H28F2N2O5S2
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 125 mg/mL (261.19 mM; Ultrasonic (<60°C)
SMILES

CC(C)S(=O)(=O)c1ccc(cc1)S(=O)(=O)N1CCC[C@H](C1)C(=O)N1CCC(F)(F)CC1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Xue D, et al. Multiparameter Optimization of Oxidative Phosphorylation Inhibitors for the Treatment of Pancreatic Cancer. J Med Chem. 2022;65(4):3404-3419. ?

Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog

Product			Quantity Required*
Name *			E-mail Address *
Organization *			Phone Number
Remarks