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Amgen-23
CAS No. 1448706-15-7
Amgen-23( —— )
Catalog No. M35699 CAS No. 1448706-15-7
Amgen-23 is a selective and highly potent sphingosine kinase 1 (SPHK1) inhibitor that inhibits SPHK2 and can be used in anticancer research.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 206 | In Stock |
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| 5MG | 188 | In Stock |
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| 10MG | 313 | In Stock |
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| 25MG | 565 | In Stock |
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| 50MG | 857 | In Stock |
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| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAmgen-23
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NoteResearch use only, not for human use.
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Brief DescriptionAmgen-23 is a selective and highly potent sphingosine kinase 1 (SPHK1) inhibitor that inhibits SPHK2 and can be used in anticancer research.
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DescriptionAmgen-23 (compound 23) is a potent sphingosine kinases (SPHK) inhibitor with IC50 values of 20 nM and 1.6 μM for SPHK1 and SPHK2, respectively. Amgen-23 can be used for researching anticancer.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayGPCR/G Protein
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TargetS1P Receptor
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RecptorS1P Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number1448706-15-7
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Formula Weight478.44
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Molecular FormulaC23H25Cl2N3O2S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (209.02 mM; Ultrasonic )
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SMILESN(C1=NC(=CS1)C2=CC(Cl)=C(Cl)C=C2)C3=CC=C(CCN4[C@@H](CO)C[C@@H](O)CC4)C=C3
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Gustin DJ, et al. Structure guided design of a series of sphingosine kinase (SphK) inhibitors. Bioorg Med Chem Lett. 2013 Aug 15;23(16):4608-16.?
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