CHD1Li 6.11
CAS No. 2716890-91-2
CHD1Li 6.11( —— )
Catalog No. M35689 CAS No. 2716890-91-2
CHD1Li 6.11 is a potent inhibitor of oncogenic CHD1L, acting on the cat-CHD1L recombinant protein (IC50: 3.3 μM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 141 | Get Quote |
|
| 5MG | 217 | Get Quote |
|
| 10MG | 353 | Get Quote |
|
| 25MG | 579 | Get Quote |
|
| 50MG | 824 | Get Quote |
|
| 100MG | 1098 | Get Quote |
|
| 500MG | 2205 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameCHD1Li 6.11
-
NoteResearch use only, not for human use.
-
Brief DescriptionCHD1Li 6.11 is a potent inhibitor of oncogenic CHD1L, acting on the cat-CHD1L recombinant protein (IC50: 3.3 μM).
-
DescriptionCHD1Li 6.11 is a potent oncogenic CHD1L inhibitor (IC50=3.3 μM for cat-CHD1L recombinant protein).CHD1Li 6.11 is an orally bioavailable antitumor agent, significantly reducing the tumor volume of CRC xenografts generated from isolated quasi mesenchymal cells (M-phenotype), which possess enhanced tumorigenic properties.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorOthers
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2716890-91-2
-
Formula Weight472.4
-
Molecular FormulaC21H22BrN5OS
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 100 mg/mL (211.69 mM; Ultrasonic )
-
SMILESCc1cc(Nc2ccc(NC(=O)Cc3cc(Br)cs3)cc2)nc(n1)N1CCCC1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Prigaro BJ, et al. Design, Synthesis, and Biological Evaluation of the First Inhibitors of Oncogenic CHD1L. J Med Chem. 2022;65(5):3943-3961. ?
molnova catalog
related products
-
3',4',5',5,7-Pentame...
It is an organic compound with fomular C20H22O7.
-
UDP-?glucuronic acid...
UDP-?glucuronic acid trisodium is a critical precursor for essential glycoconjugates across biological kingdoms, ranging from mammalian glycosaminoglycans and plant cell wall polysaccharides to bacterial capsule glycoglycerolipids.
-
Quinoline
Quinoline is found in alcoholic beverages. Quinoline is an alkaloid from various plant species including Mentha species. Also present in cocoa black tea and scotch whiskey.
Cart
sales@molnova.com