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CHD1Li 6.11

CAS No. 2716890-91-2

CHD1Li 6.11( —— )

Catalog No. M35689 CAS No. 2716890-91-2

CHD1Li 6.11 is a potent inhibitor of oncogenic CHD1L, acting on the cat-CHD1L recombinant protein (IC50: 3.3 μM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 227 In Stock
5MG 217 In Stock
10MG 353 In Stock
25MG 598 In Stock
50MG 833 In Stock
100MG 1135 In Stock
200MG Get Quote In Stock
500MG 2279 In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    CHD1Li 6.11
  • Note
    Research use only, not for human use.
  • Brief Description
    CHD1Li 6.11 is a potent inhibitor of oncogenic CHD1L, acting on the cat-CHD1L recombinant protein (IC50: 3.3 μM).
  • Description
    CHD1Li 6.11 is a potent oncogenic CHD1L inhibitor (IC50=3.3 μM for cat-CHD1L recombinant protein).CHD1Li 6.11 is an orally bioavailable antitumor agent, significantly reducing the tumor volume of CRC xenografts generated from isolated quasi mesenchymal cells (M-phenotype), which possess enhanced tumorigenic properties.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2716890-91-2
  • Formula Weight
    472.4
  • Molecular Formula
    C21H22BrN5OS
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (211.69 mM; Ultrasonic )
  • SMILES
    Cc1cc(Nc2ccc(NC(=O)Cc3cc(Br)cs3)cc2)nc(n1)N1CCCC1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Prigaro BJ, et al. Design, Synthesis, and Biological Evaluation of the First Inhibitors of Oncogenic CHD1L. J Med Chem. 2022;65(5):3943-3961. ?
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