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CHD1Li 6.11

CAS No. 2716890-91-2

CHD1Li 6.11( —— )

Catalog No. M35689 CAS No. 2716890-91-2

CHD1Li 6.11 is a potent inhibitor of oncogenic CHD1L, acting on the cat-CHD1L recombinant protein (IC50: 3.3 μM).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	227	In Stock
5MG	217	In Stock
10MG	353	In Stock
25MG	598	In Stock
50MG	833	In Stock
100MG	1135	In Stock
200MG	Get Quote	In Stock
500MG	2279	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

CHD1Li 6.11
Note

Research use only, not for human use.
Brief Description

CHD1Li 6.11 is a potent inhibitor of oncogenic CHD1L, acting on the cat-CHD1L recombinant protein (IC50: 3.3 μM).
Description

CHD1Li 6.11 is a potent oncogenic CHD1L inhibitor (IC50=3.3 μM for cat-CHD1L recombinant protein).CHD1Li 6.11 is an orally bioavailable antitumor agent, significantly reducing the tumor volume of CRC xenografts generated from isolated quasi mesenchymal cells (M-phenotype), which possess enhanced tumorigenic properties.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

——
Indication

——

Chemical Information

CAS Number

2716890-91-2
Formula Weight

472.4
Molecular Formula

C21H22BrN5OS
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (211.69 mM; Ultrasonic )
SMILES

Cc1cc(Nc2ccc(NC(=O)Cc3cc(Br)cs3)cc2)nc(n1)N1CCCC1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Prigaro BJ, et al. Design, Synthesis, and Biological Evaluation of the First Inhibitors of Oncogenic CHD1L. J Med Chem. 2022;65(5):3943-3961. ?

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