Cart
sales@molnova.com
TP-16
CAS No. 2332972-26-4
TP-16( —— )
Catalog No. M35651 CAS No. 2332972-26-4
TP-16 is a novel potent and selective EP4 antagonist that blocks the function of IMCs and enhances cytotoxic T cell-mediated tumor elimination in vivo.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 702 | Get Quote |
|
| 5MG | 1017 | Get Quote |
|
| 25MG | 1960 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameTP-16
-
NoteResearch use only, not for human use.
-
Brief DescriptionTP-16 is a novel potent and selective EP4 antagonist that blocks the function of IMCs and enhances cytotoxic T cell-mediated tumor elimination in vivo.
-
DescriptionTP-16 is a novel and selective EP4 antagonist with an IC50 of 2.1 nM.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayGPCR/G Protein
-
TargetProstaglandin Receptor
-
RecptorProstaglandin Receptor
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2332972-26-4
-
Formula Weight439.5
-
Molecular FormulaC24H22FNO4S
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESC(N[C@@H](C)C1=CC=C(C(O)=O)C=C1)(=O)C=2C3=C(SC2CC4=CC=C(F)C=C4)COCC3
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Lu W, et al. Reprogramming immunosuppressive myeloid cells facilitates immunotherapy for colorectal cancer. EMBO Mol Med. 2021 Jan 11;13(1):e12798. ?
molnova catalog
related products
-
Camonagrel
Camonagrel is a compound with inhibitory effects on Prostaglandin E2 (PGE2).
-
Treprostinil diethan...
Treprostinil diethanolamine (UT-15C) is a potent agonist of EP2, DP1, and IP, with values of 3.6, 4.4, and 32.1 nM for EP2, DP1, and IP, respectively, and 212, 826, 2505, and 4680 nM for EP1, EP4, EP3, and FPKi, respectively.
-
EP2 receptor antagon...
EP2 receptor antagonist-2 (CID891729) is a compound that blocks EP2 receptor activation by PGE2 and reduces lactate dehydrogenase (LDH) release induced by N-methyl-D-aspartate (NMDA).
