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γ-Secretase modulator 13
CAS No. 1353570-40-7
γ-Secretase modulator 13( —— )
Catalog No. M35626 CAS No. 1353570-40-7
γ-Secretase modulator 13 is a γ-secretase modulator (GSMs) that inhibits the production of amyloid β-peptide Aβ42 and can be used to study Alzheimer's disease and tumors.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 411 | In Stock |
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| 10MG | 562 | In Stock |
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| 25MG | 866 | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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Biological Information
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Product Nameγ-Secretase modulator 13
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NoteResearch use only, not for human use.
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Brief Descriptionγ-Secretase modulator 13 is a γ-secretase modulator (GSMs) that inhibits the production of amyloid β-peptide Aβ42 and can be used to study Alzheimer's disease and tumors.
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Descriptionγ-Secretase modulator 13 (compound 4) is a gamma-secretase modulator (GSMs) that inhibits the production of the aggregated amyloid β-peptide Aβ42 with an IC50 value of 163 nM. γ-Secretase modulator 13 can be used in the study of Alzheimer's disease.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayNeuroscience
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TargetGamma-secretase
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RecptorGamma-secretase
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Research Area——
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Indication——
Chemical Information
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CAS Number1353570-40-7
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Formula Weight422.52
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Molecular FormulaC22H23FN6S
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Purity>98% (HPLC)
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Solubility——
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SMILESFC=1C=C(C=CC1N2C=NC(=C2)C)C=3N=C(SC3)NC4=C5C(=NN4CC)CCCC5
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Kevin D Rynearson, et al. Design and synthesis of novel methoxypyridine-derived gamma-secretase modulators. Bioorg Med Chem. 2020 Nov 15;28(22):115734.?
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