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PI3K-IN-38

CAS No. 1382979-64-7

PI3K-IN-38( —— )

Catalog No. M35576 CAS No. 1382979-64-7

PI3K-IN-38 is an orally available and potent PI3K inhibitor with an IC50 value of 0.541 μM for PI3K-α. PI3K-IN-38 exhibits anticancer and anti-inflammatory activity and inhibits tumor growth in vivo.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    PI3K-IN-38
  • Note
    Research use only, not for human use.
  • Brief Description
    PI3K-IN-38 is an orally available and potent PI3K inhibitor with an IC50 value of 0.541 μM for PI3K-α. PI3K-IN-38 exhibits anticancer and anti-inflammatory activity and inhibits tumor growth in vivo.
  • Description
    PI3K-IN-38 (compound 123) is an orally active PI3K inhibitor with IC50 of 0.541 μM (PI3K-α). PI3K-IN-38 shows activities of anticancer and anti-inflammatory, which inhibis tumor growth in vivo.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    PI3K/Akt/mTOR signaling
  • Target
    PI3K
  • Recptor
    PI3K
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1382979-64-7
  • Formula Weight
    380.44
  • Molecular Formula
    C20H24N6O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC1(C)C2=NC=3C(N2CCO1)=NC(=NC3N4CCOCC4)C5=CC=C(N)C=C5
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Dotson J, et al. Tricyclic pi3k inhibitor compounds and methods of use. WO2012082997A1.
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