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NPR-C activator 1
CAS No. 2768328-61-4
NPR-C activator 1( —— )
Catalog No. M35566 CAS No. 2768328-61-4
NPR-C activator 1 (Compound 1) is a potent agonist (EC50 ~ 1 μM) of natriuretic peptide receptor C (NPR-C), which plays a crucial role in regulating vascular homeostasis, and demonstrates promising in vivo pharmacokinetic properties .
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 93 | In Stock |
|
| 10MG | 157 | In Stock |
|
| 25MG | 315 | In Stock |
|
| 50MG | 496 | In Stock |
|
| 100MG | 795 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameNPR-C activator 1
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NoteResearch use only, not for human use.
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Brief DescriptionNPR-C activator 1 (Compound 1) is a potent agonist (EC50 ~ 1 μM) of natriuretic peptide receptor C (NPR-C), which plays a crucial role in regulating vascular homeostasis, and demonstrates promising in vivo pharmacokinetic properties .
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DescriptionNPR-C activator 1 (Compound 1) is a potent activator of natriuretic peptide receptor C (NPR-C). C-type natriuretic peptide (CNP) is involved in the regulation of vascular homeostasis. NPR-C activator 1 is identified as a potent agonist (EC50 ～ 1 μM) with promising in vivo pharmacokinetic properties.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number2768328-61-4
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Formula Weight372.42
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Molecular FormulaC18H24N6O3
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(OC(C)(C)C)CCNC=1N=CN=C(N1)NC2=CC=C(C=C2)NC(=O)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Smith RJ, et al. A Series of Substituted Bis-Aminotriazines Are Activators of the Natriuretic Peptide Receptor C. J Med Chem. 2022 Apr 14;65(7):5495-5513.?
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