InhA-IN-4( —— )

Catalog No. M35556 CAS No. 894309-72-9

InhA-IN-4 (TU14) is a potent inhibitor of Mycobacterium tuberculosis InhA (enoyl ACP reductase), with potential anticancer and antiproliferative activities for studying Mycobacterium tuberculosis infections.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

InhA-IN-4
Note

Research use only, not for human use.
Brief Description

InhA-IN-4 (TU14) is a potent inhibitor of Mycobacterium tuberculosis InhA (enoyl ACP reductase), with potential anticancer and antiproliferative activities for studying Mycobacterium tuberculosis infections.
Description

InhA-IN-4 (TU14) is a Mycobacterium tuberculosis InhA (an enoyl ACP-reductase) inhibitor with an IC50 of 15.6 μM.
In Vitro

InhA-IN-4 (TU14) shows antitubercular activity with a MIC of 1.56 ± 0.82 μg/mL against Mycobacterium tuberculosis.
In Vivo

——
Synonyms

——
Pathway

GPCR/G Protein
Target

Antibacterial
Recptor

Antibacterial
Research Area

——
Indication

——

Chemical Information

CAS Number

894309-72-9
Formula Weight

366.23
Molecular Formula

C14H12BrN3O2S
Purity

>98% (HPLC)
Solubility

——
SMILES

C(NC(NC1=CC=C(N(=O)=O)C=C1)=S)C2=C(Br)C=CC=C2
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Do?an ?D, et al. Design and synthesis of thiourea-based derivatives as Mycobacterium tuberculosis growth and enoyl acyl carrier protein reductase (InhA) inhibitors. Eur J Med Chem. 2020 Aug 1;199:112402.?

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