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MMP2-IN-3
CAS No. 897799-81-4
MMP2-IN-3( —— )
Catalog No. M35535 CAS No. 897799-81-4
MMP2-IN-3 is a potent inhibitor of matrix metalloproteinases (MMP-2) (IC50: 31 μM). MMP2-IN-3 inhibits MMP-9 and MMP-8 with IC50s of 26.6 and 32 μM, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 143 | In Stock |
|
| 5MG | 135 | In Stock |
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| 10MG | 205 | In Stock |
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| 25MG | 333 | In Stock |
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| 50MG | 453 | In Stock |
|
| 100MG | 609 | In Stock |
|
| 200MG | 820 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameMMP2-IN-3
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NoteResearch use only, not for human use.
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Brief DescriptionMMP2-IN-3 is a potent inhibitor of matrix metalloproteinases (MMP-2) (IC50: 31 μM). MMP2-IN-3 inhibits MMP-9 and MMP-8 with IC50s of 26.6 and 32 μM, respectively.
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DescriptionMMP2-IN-3 (compound 2) is a potent MMP-2 (matrix metalloproteinases) inhibitor, with an IC50 of 31 μM. MMP2-IN-3 also shows inhibitory activity against MMP-9 and MMP-8, with IC50 values of 26.6, and 32 μM, respectively.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetMMP
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RecptorMMP
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Research Area——
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Indication——
Chemical Information
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CAS Number897799-81-4
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Formula Weight355.43
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Molecular FormulaC23H21N3O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (281.35 mM; Ultrasonic )
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SMILESN(C(CCC1=CC=CC=C1)=O)C=2C=C(C=3NC=4C(N3)=CC(C)=CC4)C=CC2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Laghezza A, et al. Virtual screening identification and chemical optimization of substituted 2-arylbenzimidazoles as new non-zinc-binding MMP-2 inhibitors. Bioorg Med Chem. 2020 Feb 1;28(3):115257. ?
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