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MRGPRX4 modulator-2

CAS No. 2492595-24-9

MRGPRX4 modulator-2( —— )

Catalog No. M35523 CAS No. 2492595-24-9

MRGPRX4 modulator-2 (compound 1-55) is a highly potent antagonist of MRGPRX4 with an IC50 value of less than 100 nM.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

MRGPRX4 modulator-2
Note

Research use only, not for human use.
Brief Description

MRGPRX4 modulator-2 (compound 1-55) is a highly potent antagonist of MRGPRX4 with an IC50 value of less than 100 nM.
Description

MRGPRX4 modulator-2 (compound 1-55) is a potent MRGPR X4 modulator, possessing antagonist activity against MRGPR X4 with an IC50 < 100 nM. MRGPRX4 modulator-2 can be used for researching autoimmune diseases such as psoriasis, multiple sclerosis, Steven Johnson’s Syndrome, and other chronic itch conditions.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

MRGPR
Research Area

——
Indication

——

Chemical Information

CAS Number

2492595-24-9
Formula Weight

348.68
Molecular Formula

C15H9ClF4O3
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 50 mg/mL (143.40 mM; Ultrasonic (<60°C)
SMILES

O=C(O)C1=CC=CC(=C1F)COC2=CC=C(C=C2Cl)C(F)(F)F
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Adam YEAGER, et al. Modulators of mas-related g-protein receptor x4 and related products and methods. WO2020198537A1 (compound 1-55)

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