Fluvastatin (XU-62320) is a potent and competitive HMG-CoA reductase inhibitor (IC50: 8 nM) that inhibits oxidative stress in vascular smooth muscle cells through an Nrf2-dependent pathway, and is used for the reduction of plasma cholesterol levels and the prevention of cardiovascular disease.

Trimethylamine N-oxide dihydrate a product of the oxidation of trimethylamine is considered as a protein stabilizer that may serve to counteract urea the major osmolyte of sharks skates and rays.

Menadione sodium bisulfite(MSB also known as vitamin K3)is used clinically in China to treat hemorrhagic diseases caused by vitamin K deficiency and globally as a vitamin K supplement.