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MAO-B-IN-9
CAS No. 2416910-88-6
MAO-B-IN-9( —— )
Catalog No. M35454 CAS No. 2416910-88-6
MAO-B-IN-9 is a monoamine oxidase B MAO-B inhibitor (IC50: 0.18 μM) that crosses the blood-brain barrier with potency, selectivity and time-dependence.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 61 | In Stock |
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| 2MG | 33 | In Stock |
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| 5MG | 53 | In Stock |
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| 10MG | 85 | In Stock |
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| 25MG | 170 | In Stock |
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| 50MG | 269 | In Stock |
|
| 100MG | 390 | In Stock |
|
| 200MG | 570 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameMAO-B-IN-9
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NoteResearch use only, not for human use.
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Brief DescriptionMAO-B-IN-9 is a monoamine oxidase B MAO-B inhibitor (IC50: 0.18 μM) that crosses the blood-brain barrier with potency, selectivity and time-dependence.
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DescriptionMAO-B-IN-9 (compound 16) is a potent, selective, BBB-penetrated, irreversible and time-dependent MAO-B (monoamine oxidase B) inhibitor, with an IC50 of 0.18 μM. MAO-B-IN-9 prevents Aβ1-42-induced neuronal cell death. MAO-B-IN-9 shows neuroprotective effects, which may be the result of its Aβ1-42 anti-aggregation effects. MAO-B-IN-9 is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMembrane Transporter/Ion Channel
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TargetBeta Amyloid
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RecptorBeta Amyloid | Monoamine Oxidase | Serotonin Transporter
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Research Area——
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Indication——
Chemical Information
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CAS Number2416910-88-6
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Formula Weight300.4
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Molecular FormulaC18H24N2O2
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Purity>98% (HPLC)
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Solubility——
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SMILESO(C(NC1=CC=C(C(C)C)C=C1)=O)C2CCN(CC#C)CC2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Ko?ak U, et al. N-alkylpiperidine carbamates as potential anti-Alzheimer's agents. Eur J Med Chem. 2020 Jul 1;197:112282. ?
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