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ELOVL1-IN-2
CAS No. 2761063-79-8
ELOVL1-IN-2( —— )
Catalog No. M35448 CAS No. 2761063-79-8
ELOVL1-IN-2, a compound known as an inhibitor of the elongation of very long chain fatty acid 1 (ELOVL1) enzyme, exhibits a weak inhibitory effect on ELOVL1 (with an IC50 of 21 μM) and demonstrates moderate potency in a primary cellular assay conducted on HEK293 C26 cells (with an IC50 of 6.7 μM) .
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 31 | In Stock |
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| 10MG | 55 | In Stock |
|
| 25MG | 112 | In Stock |
|
| 50MG | 207 | In Stock |
|
| 100MG | 310 | In Stock |
|
| 200MG | 445 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameELOVL1-IN-2
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NoteResearch use only, not for human use.
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Brief DescriptionELOVL1-IN-2, a compound known as an inhibitor of the elongation of very long chain fatty acid 1 (ELOVL1) enzyme, exhibits a weak inhibitory effect on ELOVL1 (with an IC50 of 21 μM) and demonstrates moderate potency in a primary cellular assay conducted on HEK293 C26 cells (with an IC50 of 6.7 μM) .
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DescriptionELOVL1-IN-2 is an elongation of very long chain fatty acid 1 (ELOVL1) enzyme inhibitor, ELOVL1-IN-2 shows weak ELOVL1 inhibition (IC50=21 μM) and moderate potency in a primary cellular assay (HEK293 C26 IC50=6.7 μM) .
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number2761063-79-8
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Formula Weight294.32
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Molecular FormulaC18H15FN2O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 6.67 mg/mL (22.66 mM; Ultrasonic; (HCL ，pH≈3)
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SMILESO(CCC1=CC=C(F)C=C1)C=2C=CC(=CN2)C=3C=CC=NC3
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Boyd MJ, Collier PN, Clark MP, et al. Discovery of Novel, Orally Bioavailable Pyrimidine Ether-Based Inhibitors of ELOVL1. J Med Chem. 2021;64(24):17777-17794. ?
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