Cart
sales@molnova.com
Home - Products - Metabolic Enzyme/Protease - MMP - MMP2-IN-2

MMP2-IN-2

CAS No. 1772-39-0

MMP2-IN-2( —— )

Catalog No. M35438 CAS No. 1772-39-0

MMP2-IN-2 (compound 42) is a potent and selective inhibitor of MMP-2 (matrix metalloproteinases) with an IC50 of 4.2 μM, and it also shows inhibitory activity against MMP-13, MMP-9, and MMP-8 with IC50 values of 12, 23.3, and 25 μM, respectively .

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 52 In Stock
5MG 73 In Stock
10MG 117 In Stock
25MG 220 In Stock
50MG 348 In Stock
100MG 557 In Stock
500MG 1152 In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    MMP2-IN-2
  • Note
    Research use only, not for human use.
  • Brief Description
    MMP2-IN-2 (compound 42) is a potent and selective inhibitor of MMP-2 (matrix metalloproteinases) with an IC50 of 4.2 μM, and it also shows inhibitory activity against MMP-13, MMP-9, and MMP-8 with IC50 values of 12, 23.3, and 25 μM, respectively .
  • Description
    MMP2-IN-2 (compound 42) is a potent and selective MMP-2 (matrix metalloproteinases) inhibitor, with an IC50 of 4.2 μM. MMP2-IN-2 also shows inhibitory activity against MMP-13, MMP-9 and MMP-8, with IC50 values of 12, 23.3, and 25 μM, respectively.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    MMP
  • Recptor
    MMP
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1772-39-0
  • Formula Weight
    284.23
  • Molecular Formula
    C13H8N4O4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 7.14 mg/mL (25.12 mM; Ultrasonic (<60°C)
  • SMILES
    O=[N+]([O-])C1=CC=C(C2=NC3=CC=C([N+]([O-])=O)C=C3N2)C=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Laghezza A, et al. Virtual screening identification and chemical optimization of substituted 2-arylbenzimidazoles as new non-zinc-binding MMP-2 inhibitors. Bioorg Med Chem. 2020 Feb 1;28(3):115257. ?
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • TAPI 0

    ADAM-17 (TACE) and MMP inhibitor; attenuates TNF-α processing. Acts in concert with GM6001 to inhibit Chlamydia trachomatis growth.

  • Incyclinide

    Incyclinide is a matrix metalloproteinase (MMP) inhibitor. Thereby causing extracellular matrix degradation, tumor growth and invasion, and inhibiting angiogenesis, and metastasis.

  • Ilomastat

    Ilomastat (GM6001, Galardin) is a broad spectrum matrix metalloprotease (MMP) inhibitor.

Sign In Join Free