2-C-Methyladenosine

CAS No. 15397-12-3

2-C-Methyladenosine( —— )

Catalog No. M35432 CAS No. 15397-12-3

2'-C-Methyladenosine is an inhibitor of hepatitis C virus (HCV) replication and a ribonucleoside diphosphate reductase inhibitor from Corynebacterium renalis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 29 In Stock
10MG 43 In Stock
25MG 85 In Stock
50MG 137 In Stock
100MG 212 In Stock
200MG Get Quote In Stock
500MG 533 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    2-C-Methyladenosine
  • Note
    Research use only, not for human use.
  • Brief Description
    2'-C-Methyladenosine is an inhibitor of hepatitis C virus (HCV) replication and a ribonucleoside diphosphate reductase inhibitor from Corynebacterium renalis.
  • Description
    2'-C-Methyladenosine is an inhibitor of hepatitis C virus (HCV) replication. 2'-C-Methyladenosine inhibits HCV replicon and NS5B-catalyzed RNA synthesis with IC50 values of 0.3μM and 1.9 μM, respectively. 2'-C-Methyladenosine also potently inhibits LRV1 in Leishmania guyanensis (Lgy) and Leishmania braziliensis.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    HCV Protease
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    15397-12-3
  • Formula Weight
    281.27
  • Molecular Formula
    C11H15N5O4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 31.25 mg/mL (111.10 mM; Ultrasonic (<60°C)
  • SMILES
    C[C@@]1(O)[C@H](O)[C@@H](CO)O[C@H]1n1cnc2c(N)ncnc12
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Steven S Carroll, et al. Inhibition of hepatitis C virus RNA replication by 2'-modified nucleoside analogs. J Biol Chem. 2003 Apr 4;278(14):11979-84.?
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