ROS kinases-IN-1

CAS No. 370096-57-4

ROS kinases-IN-1( —— )

Catalog No. M35383 CAS No. 370096-57-4

ROS kinases-IN-1 is a ROS tyrosine kinase inhibitor with IC50 value of 1.22 μM. ROS kinases-IN-1 shows anti-tumor activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 85 In Stock
5MG 136 In Stock
10MG 216 In Stock
25MG 358 In Stock
50MG 492 In Stock
100MG 664 In Stock
200MG 894 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    ROS kinases-IN-1
  • Note
    Research use only, not for human use.
  • Brief Description
    ROS kinases-IN-1 is a ROS tyrosine kinase inhibitor with IC50 value of 1.22 μM. ROS kinases-IN-1 shows anti-tumor activity.
  • Description
    ROS kinases-IN-1 (pag 98) is a ROS tyrosine kinase inhibitor with IC50 value of 1.22 μM. ROS kinases-IN-1 shows anti-tumor activity.
  • In Vitro
    ROS kinases-IN-1 (1-100 μM; 1 d) inhibits the growth of cervical cancer cell and glioblastoma cells.Cell Viability Assay Cell Line:HeLa, U138, U87, LN18, and U118 cells Concentration:1, 10, and 100 μM Incubation Time:one day Result:Showed EC50s for HeLa, U138, U87, LN18, and U118 cells of 20, 8, 8, 12, and 7 μM, respectively.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Immunology/Inflammation
  • Target
    ROS
  • Recptor
    ROS Kinase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    370096-57-4
  • Formula Weight
    328.37
  • Molecular Formula
    C20H16N4O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 20.83 mg/mL (63.43 mM; Ultrasonic (<60°C)
  • SMILES
    CC1=NNC(=O)\C1=C\c1cn(nc1-c1ccccc1)-c1ccccc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Dorre A. GRUENEBERG, et al. Novel methods, compounds, and compositions for inhibition of ros. WO2014141129A2.
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