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ROS kinases-IN-1
CAS No. 370096-57-4
ROS kinases-IN-1( —— )
Catalog No. M35383 CAS No. 370096-57-4
ROS kinases-IN-1 is a ROS tyrosine kinase inhibitor with IC50 value of 1.22 μM. ROS kinases-IN-1 shows anti-tumor activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 102 | In Stock |
|
| 5MG | 95 | In Stock |
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| 10MG | 151 | In Stock |
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| 25MG | 258 | In Stock |
|
| 50MG | 349 | In Stock |
|
| 100MG | 481 | In Stock |
|
| 200MG | 646 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameROS kinases-IN-1
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NoteResearch use only, not for human use.
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Brief DescriptionROS kinases-IN-1 is a ROS tyrosine kinase inhibitor with IC50 value of 1.22 μM. ROS kinases-IN-1 shows anti-tumor activity.
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DescriptionROS kinases-IN-1 (pag 98) is a ROS tyrosine kinase inhibitor with IC50 value of 1.22 μM. ROS kinases-IN-1 shows anti-tumor activity.
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In VitroROS kinases-IN-1 (1-100 μM; 1 d) inhibits the growth of cervical cancer cell and glioblastoma cells.Cell Viability Assay Cell Line:HeLa, U138, U87, LN18, and U118 cells Concentration:1, 10, and 100 μM Incubation Time:one day Result:Showed EC50s for HeLa, U138, U87, LN18, and U118 cells of 20, 8, 8, 12, and 7 μM, respectively.
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In Vivo——
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Synonyms——
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PathwayImmunology/Inflammation
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TargetROS
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RecptorROS Kinase
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Research Area——
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Indication——
Chemical Information
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CAS Number370096-57-4
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Formula Weight328.37
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Molecular FormulaC20H16N4O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 20.83 mg/mL (63.43 mM; Ultrasonic (<60°C)
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SMILESCC1=NNC(=O)\C1=C\c1cn(nc1-c1ccccc1)-c1ccccc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Dorre A. GRUENEBERG, et al. Novel methods, compounds, and compositions for inhibition of ros. WO2014141129A2.
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