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WAY-118959-A
CAS No. 315703-81-2
WAY-118959-A( —— )
Catalog No. M35317 CAS No. 315703-81-2
WAY-118959-A is a potential microtubule acetylation inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 261 | In Stock |
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| 5MG | 255 | In Stock |
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| 10MG | 375 | In Stock |
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| 25MG | 562 | In Stock |
|
| 50MG | 770 | In Stock |
|
| 100MG | 1051 | In Stock |
|
| 200MG | 1423 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameWAY-118959-A
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NoteResearch use only, not for human use.
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Brief DescriptionWAY-118959-A is a potential microtubule acetylation inhibitor.
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DescriptionGM-90257 is a microtubule acetylation inhibitor that binds directly to α-tubulin. GM-90257 prevents the recruitment of α-tubulin acetyltransferase 1 (αTAT1) to the K40 residue in α-tubulin. GM-90257 causes the apoptosis of MDA-MB-231 cells with weaker effects on MCF-10A or MCF-7 cells, which have a relatively low level of microtubule acetylation.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorMicrotubule Associated
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Research Area——
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Indication——
Chemical Information
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CAS Number315703-81-2
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Formula Weight342.44
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Molecular FormulaC16H14N4OS2
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Purity>98% (HPLC)
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Solubility——
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SMILESCOC1=CC=C(NC2=NC(=CS2)C2=C(C)N=C3SC=CN23)C=C1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Ahreum Kwon, et al. Potent Small-Molecule Inhibitors Targeting Acetylated Microtubules as Anticancer Agents Against Triple-Negative Breast Cancer. Biomedicines. 2020 Sep 9;8(9):338. ?
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