Cart
sales@molnova.com
WAY-118959-A
CAS No. 315703-81-2
WAY-118959-A( —— )
Catalog No. M35317 CAS No. 315703-81-2
WAY-118959-A is a potential microtubule acetylation inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 261 | In Stock |
|
| 5MG | 255 | In Stock |
|
| 10MG | 375 | In Stock |
|
| 25MG | 562 | In Stock |
|
| 50MG | 770 | In Stock |
|
| 100MG | 1051 | In Stock |
|
| 200MG | 1423 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameWAY-118959-A
-
NoteResearch use only, not for human use.
-
Brief DescriptionWAY-118959-A is a potential microtubule acetylation inhibitor.
-
DescriptionGM-90257 is a microtubule acetylation inhibitor that binds directly to α-tubulin. GM-90257 prevents the recruitment of α-tubulin acetyltransferase 1 (αTAT1) to the K40 residue in α-tubulin. GM-90257 causes the apoptosis of MDA-MB-231 cells with weaker effects on MCF-10A or MCF-7 cells, which have a relatively low level of microtubule acetylation.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorMicrotubule Associated
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number315703-81-2
-
Formula Weight342.44
-
Molecular FormulaC16H14N4OS2
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCOC1=CC=C(NC2=NC(=CS2)C2=C(C)N=C3SC=CN23)C=C1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Ahreum Kwon, et al. Potent Small-Molecule Inhibitors Targeting Acetylated Microtubules as Anticancer Agents Against Triple-Negative Breast Cancer. Biomedicines. 2020 Sep 9;8(9):338. ?
molnova catalog
related products
-
9,11-Dehydro-beta-bo...
9,11-Dehydro-β-boswellic acid has urease inhibitory activity. 9,11-Dehydro-beta-boswellic acid inhibiting the key enzyme of leukotriene biosynthesis, 5-lipoxygenase (5-LO).
-
VUN65671
VUN65671is a Potent Entry Inhibitor of Ebola and Marburg Virus Infections. VUN65671 was reported in Journal of Medicinal Chemistry (2020), 63(13), 7211-7225. This product has no formal name at the moment.
-
Ingenol mebutate
Ingenol mebutate is a potent activator of PKC subtypes including PKC-α, PKC-β, PKC-γ, PKC-δ, and PKC-ε with Kis of 0.3, 0.105, 0.162, 0.376, and 0.171 nM.
