VV116

CAS No. 2647442-33-7

VV116( —— )

Catalog No. M35304 CAS No. 2647442-33-7

VV116 is a selective and orally active nucleoside antiviral agent against respiratory syncytial virus and SARS-CoV-2 infection.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 141 Get Quote
5MG 217 Get Quote
10MG 345 Get Quote
25MG 635 Get Quote
50MG 899 Get Quote
100MG 1161 Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    VV116
  • Note
    Research use only, not for human use.
  • Brief Description
    VV116 is a selective and orally active nucleoside antiviral agent against respiratory syncytial virus and SARS-CoV-2 infection.
  • Description
    GS-621763-d1 is the deuterium labeled GS-621763 (HY-145119). GS-621763, an orally bioavailable proagent of GS-441524, shows antiviral activity against SARS-CoV-2 pathogenesis in mice.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    JAK/STAT Signaling
  • Target
    STAT
  • Recptor
    RSV | SARS-CoV
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2647442-33-7
  • Formula Weight
    502.54
  • Molecular Formula
    C24H30DN5O7
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (198.99 mM; Ultrasonic )
  • SMILES
    C(#N)[C@@]1([C@H](OC(C(C)C)=O)[C@H](OC(C(C)C)=O)[C@@H](COC(C(C)C)=O)O1)C=2N3C(=C(C2)[2H])C(N)=NC=N3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.?
molnova catalog
related products
  • MMPP

    MMPP is a novel VEGFR2 inhibitor with anti-inflammatory and potential anticancer activity, inhibits STAT3, inhibits angiogenesis via VEGFR2/AKT/ERK/NF-kappaB pathway, and can be used to alleviate myocardial injury.

  • PM-43I

    PM-43I is a selective inhibitor of STAT5/6 Src Homology 2 (SH2) domain.

  • FLLL-31

    FLLL-31 is a cell-permeable analog of curcumin that inhibits JAK2-mediated phosphorylation of STAT3 on Tyr705 in cancer cells.