PDD00017273( —— )

Catalog No. M35296 CAS No. 1945950-21-9

PDD00017273 is a radiosensitizing PARG) inhibitor with antitumor or activity for the study of epithelial ovaries.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	84	In Stock
5MG	71	In Stock
10MG	132	In Stock
25MG	283	In Stock
50MG	416	In Stock
100MG	600	In Stock
200MG	Get Quote	In Stock
500MG	1237	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

PDD00017273
Note

Research use only, not for human use.
Brief Description

PDD00017273 is a radiosensitizing PARG) inhibitor with antitumor or activity for the study of epithelial ovaries.
Description

PDD 00017273 is a potent inhibitor of Poly(ADP-ribose) Glycohydrolase (PARG), with an IC50 of 26 nM, and a KD of 1.45 nM.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

——
Indication

——

Chemical Information

CAS Number

1945950-21-9
Formula Weight

514.62
Molecular Formula

C23H26N6O4S2
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 25 mg/mL (48.58 mM; Ultrasonic (<60°C)
SMILES

Cc1cc(Cn2c3ccc(cc3c(=O)n(Cc3cnc(C)s3)c2=O)S(=O)(=O)NC2(C)CC2)n(C)n1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. James DI, et al. First-in-Class Chemical Probes against Poly(ADP-ribose) Glycohydrolase (PARG) Inhibit DNA Repair with Differential Pharmacology to AZD2281. ACS Chem Biol. 2016 Nov 18;11(11):3179-3190. Epub 2016 Oct 12.?

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