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PDD00017273

CAS No. 1945950-21-9

PDD00017273( —— )

Catalog No. M35296 CAS No. 1945950-21-9

PDD00017273 is a radiosensitizing PARG) inhibitor with antitumor or activity for the study of epithelial ovaries.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 84 In Stock
5MG 71 In Stock
10MG 132 In Stock
25MG 283 In Stock
50MG 416 In Stock
100MG 600 In Stock
200MG Get Quote In Stock
500MG 1237 In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    PDD00017273
  • Note
    Research use only, not for human use.
  • Brief Description
    PDD00017273 is a radiosensitizing PARG) inhibitor with antitumor or activity for the study of epithelial ovaries.
  • Description
    PDD 00017273 is a potent inhibitor of Poly(ADP-ribose) Glycohydrolase (PARG), with an IC50 of 26 nM, and a KD of 1.45 nM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1945950-21-9
  • Formula Weight
    514.62
  • Molecular Formula
    C23H26N6O4S2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 25 mg/mL (48.58 mM; Ultrasonic (<60°C)
  • SMILES
    Cc1cc(Cn2c3ccc(cc3c(=O)n(Cc3cnc(C)s3)c2=O)S(=O)(=O)NC2(C)CC2)n(C)n1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. James DI, et al. First-in-Class Chemical Probes against Poly(ADP-ribose) Glycohydrolase (PARG) Inhibit DNA Repair with Differential Pharmacology to AZD2281. ACS Chem Biol. 2016 Nov 18;11(11):3179-3190. Epub 2016 Oct 12.?
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