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BMS202 hydrochloride (1675203-84-5(free base))

CAS No. 2089334-95-0

BMS202 hydrochloride (1675203-84-5(free base))( —— )

Catalog No. M35287 CAS No. 2089334-95-0

BMS202 hydrochloride (1675203-84-5(free base)) (PD-1/PD-L1 inhibitor 2 hydrochloride) is a small-molecule PD-1/PD-L1 interaction inhibitor (IC50: 18 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    BMS202 hydrochloride (1675203-84-5(free base))
  • Note
    Research use only, not for human use.
  • Brief Description
    BMS202 hydrochloride (1675203-84-5(free base)) (PD-1/PD-L1 inhibitor 2 hydrochloride) is a small-molecule PD-1/PD-L1 interaction inhibitor (IC50: 18 nM).
  • Description
    BMS202 hydrochloride (1675203-84-5(free base)) (PD-1/PD-L1 inhibitor 2 hydrochloride) is a small-molecule PD-1/PD-L1 interaction inhibitor (IC50: 18 nM). Biophysical studies demonstrate that BMS202 binds directly to PD-L1. Binding of BMS202 promotes PD-L1 dimerisation and blocks the PD-L1/ PD1 interaction.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Immunology/Inflammation
  • Target
    PD-1/PD-L1
  • Recptor
    PD-1/PD-L1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2089334-95-0
  • Formula Weight
    455.97
  • Molecular Formula
    C25H30ClN3O3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Cl.COc1nc(OCc2cccc(c2C)-c2ccccc2)ccc1CNCCNC(C)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

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