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UZH2
CAS No. 2756566-45-5
UZH2( —— )
Catalog No. M35203 CAS No. 2756566-45-5
UZH2 is a potent and selective METTL3 inhibitor with an IC50 value of 5 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 297 | In Stock |
|
| 10MG | 471 | In Stock |
|
| 25MG | 739 | In Stock |
|
| 50MG | 918 | In Stock |
|
| 100MG | 1265 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 2539 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameUZH2
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NoteResearch use only, not for human use.
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Brief DescriptionUZH2 is a potent and selective METTL3 inhibitor with an IC50 value of 5 nM.
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DescriptionUZH2 is a potent and selective METTL3 inhibitor with an IC50 value of 5 nM.
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In VitroWestern Blot Analysis Cell Line:MOLM-13 cells Concentration:0-25 μM Incubation Time:1h Result:Stabilized METTL3 in a dosedependent manner at 54 °C.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number2756566-45-5
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Formula Weight513.63
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Molecular FormulaC27H37F2N7O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 50 mg/mL (97.35 mM; Ultrasonic )
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SMILESCNc1cc(ncn1)N1CCC2(CC1)CN(CC(=O)N2)c1cc(F)c(CN2CCC(C)(C)CC2)cc1F
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Dolbois A, et al. 1,4,9-Triazaspiro[5.5]undecan-2-one Derivatives as Potent and Selective METTL3 Inhibitors. J Med Chem. 2021 Sep 9;64(17):12738-12760. ?
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