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B-Raf IN 2

CAS No. 2649372-20-1

B-Raf IN 2( —— )

Catalog No. M35194 CAS No. 2649372-20-1

B-Raf IN 2, compound Ia, is a highly effective and specific inhibitor of BRAF. It exhibits significant potential for cancer research.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    B-Raf IN 2
  • Note
    Research use only, not for human use.
  • Brief Description
    B-Raf IN 2, compound Ia, is a highly effective and specific inhibitor of BRAF. It exhibits significant potential for cancer research.
  • Description
    B-Raf IN 2 is a potent and selective BRAF inhibitor extracted from patent WO2021116055A1, compound Ia. B-Raf IN 2 can be used for the research of cancer.
  • In Vitro
    B-Raf IN 2 shows considerably less paradoxial activation of the MAPK signaling pathway while retaining high potency.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    MAPK/ERK Signaling
  • Target
    Raf
  • Recptor
    Raf
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2649372-20-1
  • Formula Weight
    461.44
  • Molecular Formula
    C20H17F2N5O4S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (216.71 mM; Ultrasonic )
  • SMILES
    Cn1cnc2ccc(Oc3c(F)ccc(NS(=O)(=O)N4CC[C@@H](F)C4)c3C#N)cc2c1=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Dolente C, et, al. New methylquinazolinone derivatives. WO2021116055A1.
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