Home - Products - MAPK/ERK Signaling - Raf - B-Raf IN 2

B-Raf IN 2

CAS No. 2649372-20-1

B-Raf IN 2( —— )

Catalog No. M35194 CAS No. 2649372-20-1

B-Raf IN 2, compound Ia, is a highly effective and specific inhibitor of BRAF. It exhibits significant potential for cancer research.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
5MG	121	In Stock
10MG	188	In Stock
25MG	335	In Stock
50MG	460	In Stock
100MG	647	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

Get Quotation Bulk Inquiry Add to Cart

Biological Information

Product Name

B-Raf IN 2
Note

Research use only, not for human use.
Brief Description

B-Raf IN 2, compound Ia, is a highly effective and specific inhibitor of BRAF. It exhibits significant potential for cancer research.
Description

B-Raf IN 2 is a potent and selective BRAF inhibitor extracted from patent WO2021116055A1, compound Ia. B-Raf IN 2 can be used for the research of cancer.
In Vitro

B-Raf IN 2 shows considerably less paradoxial activation of the MAPK signaling pathway while retaining high potency.
In Vivo

——
Synonyms

——
Pathway

MAPK/ERK Signaling
Target

Raf
Recptor

Raf
Research Area

——
Indication

——

Chemical Information

CAS Number

2649372-20-1
Formula Weight

461.44
Molecular Formula

C20H17F2N5O4S
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (216.71 mM; Ultrasonic )
SMILES

Cn1cnc2ccc(Oc3c(F)ccc(NS(=O)(=O)N4CC[C@@H](F)C4)c3C#N)cc2c1=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Dolente C, et, al. New methylquinazolinone derivatives. WO2021116055A1.

Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog

related products

Kobe0065

Kobe0065 is a novel and effective small-molecule compound inhibiting Ras–Raf interaction by SBDD.
Kobe2602

kobe2602 is a novel and effective small-molecule compound inhibiting Ras–Raf interaction by SBDD.
Uplarafenib

Uplarafenib (B-Raf IN 10) is a potent BRAF inhibitor with an IC50 of 50-100 nM. B-Raf IN 10 exhibits antitumor activity that may influence cell proliferation and differentiation, making it suitable for studying solid tumors.

Sign In Join Free